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Los Angeles, also simply known as L.A., is a major city in California. The second most populous city in the United States, behind only New York City, Los Angeles is home to such neighborhoods as Hollywood, Santa Monica, and the San Fernando Valley.

Initially set to serve as the major backdrop for the proposed Gossip Girl prequel series, Valley Girls, Los Angeles serves as a secondary location for the Gossip Girl television adaption, appearing in the season four premiere, "Yes, Then Zero."

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