Rufus Humphrey is a former rock artist whose marriage fell apart. He has two children, Dan and Jenny Humphrey, and owns a fledgling art gallery. Determined to give his children a quality education, he enrolled them at private day schools in Manhattan, leading him to run into a former flame, Lily van der Woodsen. He has difficulty being a single parent managing his children as they are growing. In the second season finale, Lily and Rufus became engaged and married in the fifth episode of the third season.
Rufus is a very honest man. He is not constantly caught up in the drama of the Upper East Side, and he is not the center of many intricate plot twists, but he is without a doubt one of the most purely good person in Upper Manhattan. Not only is he dedicated to truth and honesty, but he is also fiercely loyal. No matter how many times Lily lets him down, Rufus displays an unwavering sense of devotion to her. He fights for the people he loves, no matter what, and he always makes the people in his life feel valuable. The people he is closest to never doubt that he cares for them. He is generous, thoughtful, and creative, with a great sense of humor.
- Lily Bass Humphrey (Ex-Wife)
- Alison Humphrey (Ex-Wife)
- Dan Humphrey (Son)
- Jenny Humphrey (Daughter)
- Serena Van der Woodsen (Ex-Step-Daughter)
- Eric Van der Woodsen (Ex-Step-Son)
- Scott Rosson (Son, Adopted out of family)
- Chuck Bass (Ex-Step-Son)
- CeCe Rhodes (Ex-Mother In-Law)
- Carol Rhodes (Ex-Sister In-Law)
- Charlie Rhodes (Ex-Niece)